RESEARCH PROGRESS ON THE SYNTHESIS OF 4-HYDROXY-2,5-DIMETHYL-3(2H)-FURANONE BY MICROORGANISMS

Research progress on the synthesis of 4-hydroxy-2,5-dimethyl-3(2H)-furanone by microorganisms

Research progress on the synthesis of 4-hydroxy-2,5-dimethyl-3(2H)-furanone by microorganisms

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4-hydroxy-2,5-dimethyl-3(2H)-furanone (HDMF) is a safe and excellent sweet flavor and aroma agent with caramel taste, which has 15-eg2373cl a lower threshold, good fragrance potential, and strong characteristics, which is widely used in food, tobacco, and other products, and the market demand is large, especially for natural sources of HDMF.However, the yield of natural HDMF is low and cannot meet the current market demand.For this reason, the application, detection, production methods, species of microorganisms that synthesize HDMF, mechanism of microbial synthesis of HDMF, and key enzymes as well as influencing factors of fermentation culture conditions were briefly reviewed.The main focus was on the microorganisms species that have been reported to synthesize HDMF, the internal mechanism of microbial synthesis of HDMF and the culture factors affecting its fermentation, aiming to provide moen finney a reference for subsequent screening, modification and obtaining excellent and high-yield HDMF strains, and optimize the microbial fermentation conditions to achieve efficient preparation of natural HDMF by biological methods.

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